https://ogma.newcastle.edu.au/vital/access/ /manager/Index ${session.getAttribute("locale")} 5 PAI-1 augments mucosal damage in colitis https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:47717 Wed 25 Jan 2023 13:01:40 AEDT ]]> Comment on "PP2A inhibition sensitizes cancer stem cells to ABL tyrosine kinase inhibitors in BCR-ABL human leukemia" https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:48375 Wed 15 Mar 2023 13:47:42 AEDT ]]> Neurokinin 1 receptor signaling in endosomes mediates sustained nociception and is a viable therapeutic target for prolonged pain relief https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:34617 Wed 09 Feb 2022 15:55:15 AEDT ]]> A Persistent Neutrophil-Associated Iimmune Signature Characterizes Post-COVID-19 Pulmonary Sequelae https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:50423 Tue 25 Jul 2023 18:33:24 AEST ]]> Pathophysiological regulation of lung function by the free fatty acid receptor FFA4 https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:41995 Tue 16 Aug 2022 16:37:18 AEST ]]> Type 2 immune polarization is associated with cardiopulmonary disease in preterm infants https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:51168 Thu 24 Aug 2023 14:09:35 AEST ]]> microRNA-21-mediated SATB1/S100A9/NF-kappa B axis promotes chronic obstructive pulmonary disease pathogenesis https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:49088 Thu 04 May 2023 13:43:05 AEST ]]> Inhaled corticosteroid suppression of cathelicidin drives dysbiosis and bacterial infection in chronic obstructive pulmonary disease https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:42308 Camp-/-) and exogenous cathelicidin prevented ICS-mediated expansion of streptococci within the microbiota and improved bacterial clearance. Suppression of pulmonary immunity by ICS was mediated by augmentation of the protease cathepsin D. Collectively, these data suggest a central role for cathepsin D/cathelicidin in the suppression of antibacterial host defense by ICS in COPD. Therapeutic restoration of cathelicidin to boost antibacterial immunity and beneficially modulate the lung microbiota might be an effective strategy in COPD.]]> Mon 22 Aug 2022 10:35:15 AEST ]]>